Histones preserve cell memories

Free Histones and the Cell Cycle

Antigen-induced Changes in Lymphoid Cell Histones

The nuclear histones of control and antigen-affected lymphocytes and thymocytes were measured in terms of their intensity of staining with ammoniacal-silver (A-S) and alkaline fast green (FG). Subcutaneous injection of full strength and doubly concentrated tetanus toxoid into the upper forelimb was followed by an acute decrease in the intensity of the FG and A-S staining of the thymocyte nuclea...

Histones

JAUNDICE DURING PREGNANCY. By Urs Peter Haemmerli. New York, Springer-Verlag, Inc., 1967. 111 pp. $3.80, paperbound. Jaundice During Pregnancy is an excellent monograph which should be read by all internists, obstetricians, and pediatricians, and which should be available in all medical libraries for ready reference. The author concisely summarizes the known minor alterations of the liver and i...

Exploiting Histones

Book Review charged amino acids which appear to follow the path Exploiting Histones of the DNA helix. These interactions and the preferred direction of DNA bending by specific sequences (Chap-Chromatin Structure and Gene Expression. ter 2) undoubtedly contribute to nucleosome positioning Edited by Sarah C. R. Elgin. in some manner. Chapter 1 also makes it clear that New York: IRL Press. (1995)....

Generation and management of excess histones during the cell cycle.

Histones are essential proteins that package the DNA in all eukaryotes into chromosomes. However, histones can accumulate upon a decrease in DNA synthesis that occurs at the end of S-phase or following replication arrest. These positively charged histones can associate non-specifically with the negatively charged DNA and other cellular biomolecules, impairing their normal function. Hence, cells...